HLA-B51 is a genetic marker that belongs to the Human Leukocyte Antigen (HLA) system, which plays an important role in the immune system by identifying foreign cells and attacking them. HLA-B51 is found in the major histocompatibility complex (MHC) class I region of the genome and is primarily associated with increased risk for certain autoimmune diseases, such as Behcet's disease, a rare inflammatory disorder that affects multiple organs. However, it is important to note that having the HLA-B51 gene does not necessarily mean that an individual will develop these diseases, as other environmental and genetic factors may also be involved. HLA-B51 testing can be ordered in certain cases to help diagnose these conditions and guide treatment decisions.
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